Sugarcoating ER Stress
نویسندگان
چکیده
The hexosamine biosynthetic pathway (HBP) generates metabolites for protein N- and O-glycosylation. Wang et al. and Denzel et al. report a hitherto unknown link between the HBP and stress in the endoplasmic reticulum. These studies establish the HBP as a critical component of the cellular machinery of protein homeostasis.
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عنوان ژورنال:
- Cell
دوره 156 شماره
صفحات -
تاریخ انتشار 2014